Intestinal Absorption Mechanisms of .BETA.-Lactam Antibiotics.
نویسندگان
چکیده
منابع مشابه
Beta-Lactam Antibiotics and Vancomycin Beta-lactam antibiotics
Anti-bacterial drugs have “selective toxicity”, that is they interact with a target present on the bacterial cell, the prokaryote, that is not present in the mammalian host, the eukaryote. For the ß-lactam drugs, this target is the cell wall. Mammalian cells lack cell walls, which for the bacteria are a critically important barrier protecting the organism from not only the vagaries of osmotic s...
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Humans have been plagued with the threat of bacterial infection since before the dawn of recorded history, and have thus always had a keen interest in finding a suitable treatment for these maladies. In the early part of the 19th century, colonial Americans were fearful of death by bacterial infections that are now considered routine, and usually inquired about one another's health in their let...
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BUMC PROCEEDINGS 2001;14:106–107 D uring a drug history, the most common drug allergies cited are those experienced after the administration of a penicillin, with a reported allergy incidence of 1% to 10% in patients who receive drugs in this class (1). Penicillins, as well as other beta-lactam antibiotics such as cephalosporins, carbapenems, and monobactams, contain a beta-lactam ring (2). The...
متن کاملthe survey of genes encoding beta-lactamases, in escherichia coli resistant to beta-lactam and non-beta-lactam antibiotics
objective(s) resistance to the new generation of cephalosporins which is mediated by extended-spectrum beta-lactamases (esbls) has been found among escherichia coli isolates throughout the world. these resistance genes and their producers, the micro-organisms carrying beta-lactamases, are responsible for serious clinical and therapeutic problems among inpatients and it is necessary to pay more ...
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ژورنال
عنوان ژورنال: Drug Metabolism and Pharmacokinetics
سال: 1999
ISSN: 0916-1139
DOI: 10.2133/dmpk.14.171